Sarcopenia in chronic liver diseases: a translational overview
Abstract
Introduction: Sarcopenia refers to a progressive and generalized muscle mass and strength loss. In liver diseases, it has been related to worse outcomes and high risk of decompensations.
Immunization with neural-derived peptides increases neurogenesis in rats with chronic spinal cord injury
Abstract
Aims: Immunization with neural-derived peptides (INDP) has demonstrated to be a promising therapy to achieve a regenerative effect in the chronic phase of the spinal cord injury (SCI). Nevertheless, INDP-induced neurogenic effects in the chronic stage of SCI have not been explored.
In vitro bactericidal activity of a carbohydrate polymer with zinc oxide for the treatment of chronic wounds
Abstract
Introduction. Biological adhesives and effective topical therapeutic agents that improve wound healing are urgently required for the treatment of chronic ulcers. A biodegradable adhesive based on a carbohydrate polymer with zinc oxide (CPZO) was shown to possess anti-inflammatory activity and enhance wound healing, but its bactericidal activity was unknown. Aim. To investigate the bactericidal activity of CPZO against bacteria commonly present as infectious agents in chronic wounds.
A meta-review of literature reviews assessing the capacity of patients with severe mental disorders to make decisions about their healthcare
Abstract
Background
Determining the mental capacity of psychiatric patients for making healthcare related decisions is crucial in clinical practice. This meta-review of review articles comprehensively examines the current evidence on the capacity of patients with a mental illness to make medical care decisions.
Cost evaluation of point-of-care testing for community-acquired influenza in adults presenting to the emergency department
Abstract
Background: Rapid molecular point-of-care tests (POCTs) for influenza have potential to produce cost savings in emergency departments (EDs) and acute care settings. To date, published projected savings have been based on estimated costs.
Supraspinal and Afferent Signaling Facilitate Spinal Sensorimotor Network Excitability After Discomplete Spinal Cord Injury: A Case Report
Abstract
Objective: In this study, we evaluated the role of residual supraspinal and afferentsignaling and their convergence on the sublesional spinal network in subject diagnosed with complete paralysis (AIS-A).