Relationship between rs4349859 and rs116488202 polymorphisms close to MHC-I region and serum urate levels in patients with gout
Abstract
Gout is the most common inflammatory rheumatic disease and elevated levels of serum urate (SU) are the main cause for its development. Major histocompatibility complex class 1 (MHC-1) plays an important role in the development of multiple inflammatory diseases; however, there is little evidence of its involvement in gout. The present study focused on evaluating the association of the rs4349859 and rs116488202 single nucleotide polymorphisms (SNPs) close to the MHC-1 region in patients with gout.
Tacubaya Hydric District, Ciudad de México, 2022. A Medium-scale Urban Model for Sustainable Water Management in Mexico city
Abstract
As a response to the water crisis in Mexico City, Tacubaya Hydric District proposes a sustainable and decentralized water management system that integrates green and gray infrastructure to valorize urban waters -rainwater, graywater, and blackwater- as a resource rather than waste. © 2023, Pontificia Universidad Catolica de Chile. All rights reserved.